Recruitment, Retention, and Representation: Africa’s Participant Diversity Problem
A clinical trial can reach its enrollment target and still produce evidence that is too narrow for the population it is intended to serve. The headline number may look reassuring, but it does not reveal whether the cohort reflects the relevant differences in age, sex,...
Advancing Africa-Led Research to Prevent Mother-to-Child HIV Transmission
Africa Clinical Research Network awarded grant to lead SUPPRESS-LA, a Phase 3 trial evaluating long-acting antiretroviral therapy to prevent mother-to-child HIV transmission Africa-led, multicountry study in South Africa, Uganda and Zimbabwe will evaluate whether...
The African Medicines Agency: What Continental Regulatory Harmonization Actually Changes
A multi-country clinical trial can follow one protocol, test one investigational product, and pursue one scientific question, yet encounter different submission formats, review requirements, amendment procedures, and decision timelines in every participating country. ...
Pharmacovigilance and Post-Market Surveillance: Africa’s Safety Blind Spot
A medicine may complete clinical trials with an acceptable safety profile and still reveal important risks only after thousands, or millions, of people begin using it. Approval is not the end of safety assessment. It is the point at which monitoring must expand from a...
Decentralized and Digital Trials: What’s Realistic in African Settings
A video consultation can replace a clinic visit. It cannot replace clinical judgment, reliable connectivity, regulatory oversight, or accountable data governance. That distinction is often blurred in discussions about decentralized clinical trials (DCTs). Remote...
Local Manufacturing and Clinical Trials: Closing Africa’s Development-to-Production Gap
The final participant visit is usually treated as the end of a clinical trial. For Africa’s health-product economy, it should be a handover point: the moment when evidence begins to inform regulatory approval, manufacturing, procurement and delivery. African...
From Projects to Platforms: Why Africa’s Clinical Research Future Depends on Institutional Models
A clinical trial can leave behind a valuable dataset, a published paper and a team with new experience. It can also leave behind an empty office, expired service contracts, underused equipment and research professionals searching for the next grant. The difference is...
𝐀𝐂𝐑𝐍 𝐚𝐧𝐝 𝐅𝐏-𝐈𝐂𝐆𝐋𝐑 𝐄𝐬𝐭𝐚𝐛𝐥𝐢𝐬𝐡 𝐋𝐚𝐧𝐝𝐦𝐚𝐫𝐤 𝐑𝐞𝐠𝐢𝐨𝐧𝐚𝐥 𝐏𝐚𝐫𝐭𝐧𝐞𝐫𝐬𝐡𝐢𝐩
The three-year agreement creates the first regional parliamentary framework dedicated to advancing evidence-informed clinical research policy, health innovation and stronger health systems across the Great Lakes Region. KINSHASA, Democratic Republic of the Congo, and...